A 57-year-old alcoholic woman with soft neck mass





Launois-Bensaude syndrome, Madelung’s disease, Multiple symmetric lipomatosis, Surgical treatment


A 57-year-old woman was diagnosed with an anterior cervical mass (figure 1). No peripheral neuropathy or cervical lymph nodes were detected from the physical examination. The mass has slowly and painlessly grown for 30 years with no dyspnea or dysphagia. She had a history of chronic alcohol consumption and heavy tobacco use for 25 years. No standard medications were taken.

Multiple symmetric lipomatosis is a disease characterized by the accumulation of multiple, benign, symmetric, and nonencapsulated fatty tissue masses. This is more common in males (15:1) and in the Mediterranean population. Malignancy is rarely observed in this case. Masses can be found on the head and neck, including the upper trunk, shoulders, upper back, mediastinum, perineum, scrotum, and tongue. Besides the aesthetic effects, masses can cause airways or digestive compressive symptoms, as well as limitations in head or neck movements, urinating, or sexual intercourse. The involvement of peripheral nerves can cause neurological symptoms.


Alcohol abuse has been long associated with this disease.  A genetic cause has been suggested, but a hereditary pattern has not been identified in most cases. A link was suggested with liver disease, but there is no mention of liver abscess in the literature.


The diagnostic is based on image finds. Solitary lipoma is a benign soft tissue tumor, rarely found in the neck region. It mostly occurs in females and obese patients, and it is enclosed by a fibrous capsule that helps to differentiate it from other fat aggregations. Liposarcoma represents 1% of neck and head sarcomas. Patients are mostly men and the medium age is 70 years. Familial multiple lipomatosis is a rare autosomal dominant disease that is manifested in the thirties and is more prevalent in females (2:1). In this case, the discrete multiple subcutaneous nodules are movable, painless, and soft and have no associated conditions.


Lipectomy is the concerned treatment, but recurrence is common. Liposuction is an alternative to extensive lipectomy. No medicinal therapy is effective; however, alcohol abstinence can reduce the recurrence frequency.


Clinics must be aware of this uncommon disease in order to diagnose it and treat it appropriately.


Statement of Ethics

Written informed consent was obtained from the patient for publication of this case report and any accompanying images.


Conflict of Interest Statement

The authors have no conflicts of interest to declare.


Funding Sources

The authors had no funding sources in the preparation of data or the manuscript.


Não há dados estatísticos.

Biografia do Autor

Ana Clara Galindo Miranda, Oswaldo Cruz University Hospital, University of Pernambuco, Recife, Brazil

Estudante de Medicina da Faculdade de Ciências Médicas, Universidade de Pernambuco. Fui aprovada pelo vestibular seriado, não cotista, em 2016 e dedico-me desde o primeiro ano do ensino superior a ações de pesquisa e apresentação de trabalhos científicos. Tenho trabalhos apresentados e publicados no exterior e no Brasil, além de um capítulo de livro publicado. Tenho especial interesse pela carreira acadêmica.

Matheus Stillner Eufranio, Oswaldo Cruz University Hospital, University of Pernambuco, Recife, Brazil

Acadêmico de medicina da Universidade de Pernambuco. Integrante do grupo Muito além do Gessos que auxilia ortopedistas e aspirantes a ortopedistas a desenvolverem sua trajetória. Possui em interesse em Pesquisa.

Maria Vitória Rocha Santos Bezerra Maia, Oswaldo Cruz University Hospital, University of Pernambuco, Recife, Brazil

Acadêmica do 8º período da Faculdade de Ciências Médicas da Universidade de Pernambuco (FCM/UPE). Pesquisadora do Grupo de Pesquisa biomarcadores de doenças cardiovasculares do PROCAPE (Pronto-Socorro Cardiológico de Pernambuco), liderado pelo Dr. José Gildo de Moura Monteiro Junior e orientada pelo Prof. Dr.Luiz Eduardo Correia Miranda. Membro da Liga Acadêmica de Cirurgia Geral da Universidade de Pernambuco. Extensionista pelo projeto Entrelaçados - Palhaçoterapia e pelo projeto Superando a Obesidade, ambos vinculados à pro-reitoria de extensão da UPE. Certificação pela Universidade de Cambrigde nível First Certificate of English (FCE).




Como Citar

Miranda LEC, Miranda ACG, Eufranio MS, Maia MVRSB. A 57-year-old alcoholic woman with soft neck mass. am [Internet]. 31º de janeiro de 2022 [citado 23º de setembro de 2023];1(4):163-4. Disponível em: https://www.jornalavancosmedicina.com/index.php/am/article/view/58




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